• For stalled wounds when antimicrobial properties of silver are desired.
• 100% collagen with a high degree of nativity ^1,2
• High gel integrity³
• Helps promote natural healing
• Jump-starts stalled wounds^4,5,6
• Ionic silver provides antimicrobial barrier^8,9
• Indications: pressure, venous, diabetic ulcers, partial and full-thickness wounds, ulcers caused by mixed vascular etiologies, burns, donor sites and other surface wounds, abrasions, traumatic wounds healing by secondary intention and dehisced surgical wounds.
• Contraindicated for active vasculitis or patients with known sensitivity to collagen or silver.
• May be left in place for up to 7 days.
• Dressing change frequency will depend on amount of drainage.

1. Data on file.
2. Picrosirius Assay to Determine Relative Nativity of Two Collagenous Dressings, internal report. 
3. Comparative Physical Properties of Two Collagenous Dressings, Promogran and Puracol Plus, data on file.
4. Driver V, French M, Cain J, Hagen H, Hijazin M, Patel M. The Use of Native Collagen Dressings on Chronic Lower Extremity Wounds: Case Studies. Presented at SAWC. Tampa, FL. 2007.
5. A Clinical Safety and Efficacy Evaluation on Seriously Chronic Wounds with a Native Collagen Dressing, data on file.
6. Rogers LC, Armstrong DG. The promise of stem cells. Podiatry Management. June/July 2007:65-70.
7. Fliegel S et al. Collagen Degradation in Aged/ Photodamaged Skin In Vivo and After Exposure to Matrix Metalloproteinase-1 In Vitro. J Invest Dermatol 12: 842-848, 2003.
8. Sibbald RG et al, Increased bacterial burden and infection, the story of NERDS and STONES, Advances in Skin and Wound Care 19: 447-61, 2006. 
9. The antimicrobial benefits of silver and the relevance of Microlattice® technology. Ostomy/Wound Management. 49 (2A), 4-7, 2003.

• Puracol Plus Ag with antimicrobial silver is 100% pure native collagen, no fillers added.
• It's pure bovine-derived collagen in its native, triple-helix format.
• Helps restore chemical balance in the wound bed.
• Collagen dressings facilitate the give and take magnetism of a healing wound, supporting normal fibroblast activity while distracting negative forces like MMP's and Elastase.
• Triple helix structure allows body's own fibroblasts to act normally.
• Fibroblasts recognize this structure as natural, so they behave normally producing the collagen to heal the wound.